Antimicrobial rationing in orthopaedic surgery

Local Antimicrobial Treatment in Orthopaedic Surgery

The purpose of this special issue of Journal of Bone and Joint Infection is to provide orthopaedic surgeons with basic science explanations as to how these local antimicrobials work, clinical evidence that supports these local treatments, and the role of these local treatments against biofilm.

Antimicrobial prophylaxis in orthopaedic surgery: the role of teicoplanin.

Orthopaedic joint replacement is generally considered 'clean' surgery characterized by a low incidence of infection. In recent years the use of a clean theatre environment, high local concentrations of antibiotic in the cement and systemic antibiotic prophylaxis have been recognized as important measures to reduce infection rates significantly, and this has been supported by clinical trials. St...

Orthopaedic surgery.

Ethics in orthopaedic surgery.

©2005 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.87B11. 16936 $2.00 J Bone Joint Surg [Br] 2005;87-B:1449-51. Medicine, law and religion are the three traditional learned professions. With professionalism should come both privilege and responsibility. As surgeons we study to achieve specialised knowledge and supplement this with training and experience. Our patien...

Ximelagatran in orthopaedic surgery.

Ximelagatran represents the first new oral anticoagulant since the introduction of warfarin almost 60 years ago, and has been evaluated for the treatment and prevention of a range of venous and arterial thromboembolic disorders. The MElagatran THRomboprophylaxis in Orthopaedic surgery (METHRO) and EXpanded PRophylaxis Evaluation Surgery Study (EXPRESS) studies have investigated the efficacy and...